Protein-bound solute removal during extended multipass versus standard hemodialysis

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Protein-bound solute removal during extended multipass versus standard hemodialysis

BACKGROUND Multipass hemodialysis (MPHD) is a recently described dialysis modality, involving the use of small volumes of dialysate which are repetitively recycled. Dialysis regimes of 8 hours for six days a week using this device result in an increased removal of small water soluble solutes and middle molecules compared to standard hemodialysis (SHD). Since protein-bound solutes (PBS) exert im...

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Contribution of residual function to removal of protein-bound solutes in hemodialysis.

BACKGROUND AND OBJECTIVES This study evaluated the contribution of residual function to the removal of solutes for which protein binding limits clearance by hemdialysis. DESIGN, SETTING, PARTICIPANTS, & MEASUREMENTS Solute concentrations were measured in 25 hemodialysis patients with residual urea clearances ranging from 0.1 to 6.2 ml/min per 1.73 m2. Mathematical modeling assessed the effect...

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Once-weekly hemodialysis helps continuous ambulatory peritoneal dialysis patients who have insufficient solute removal.

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ژورنال

عنوان ژورنال: BMC Nephrology

سال: 2015

ISSN: 1471-2369

DOI: 10.1186/s12882-015-0056-y